Carregant...
Carregant...

Vés al contingut (premeu Retorn)

Viral replication modes in single-peak fitness landscapes: A dynamical systems analysis

Autor
Forners, J.; Lazaro, J. Tomás; Alarcón, T.; F. Elena, S.; Sardanyes, J.
Tipus d'activitat
Article en revista
Revista
Journal of theoretical biology
Data de publicació
2019-01-07
Volum
460
Pàgina inicial
170
Pàgina final
183
DOI
https://doi.org/10.1016/j.jtbi.2018.10.007 Obrir en finestra nova
Repositori
http://hdl.handle.net/2117/125463 Obrir en finestra nova
URL
https://www.sciencedirect.com/science/article/pii/S0022519318304776?via%3Dihub Obrir en finestra nova
Resum
Positiv e-sense, single-stranded RN A viruses are im portant pathogens infecting almost all types of organ- isms. Experimental evidence from distributions of mutations and from viral RN A ampli¿cation suggest that these pathogens may follow different RN A replication modes, r anging from the stamping machine replication (SMR) to the geo metric replication (GR) mode. Although previous theoretical work has focuse d on the evolutionary dynamics of RNA viruses amplifying their genomes with dif fer ...
Paraules clau
Bifurcations, Dynamical systems, Error threshold, RNA viruses, Replication modes, Single-peak fitness landscape
Grup de recerca
SD - Sistemes Dinàmics de la UPC

Participants

  • Forners, Joan  (autor)
  • Lazaro Ochoa, Jose Tomas  (autor)
  • Alarcón, Tomás  (autor)
  • F. Elena, Santiago  (autor)
  • Sardanyes, Josep  (autor)