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Plasma polymerized bioceramics for drug delivery: Do surface changes alter biological behaviour?

Autor
Khurana, K.; Müller, F.; Jacobs, K.; Canal, C.; Ginebra, M.P.
Tipus d'activitat
Article en revista
Revista
European polymer journal
Data de publicació
2018-10-01
Volum
107
Pàgina inicial
25
Pàgina final
33
DOI
https://doi.org/10.1016/j.eurpolymj.2018.07.016 Obrir en finestra nova
Repositori
http://hdl.handle.net/2117/125163 Obrir en finestra nova
URL
https://www.sciencedirect.com/science/article/pii/S0014305718304130 Obrir en finestra nova
Resum
One of the treatments for recurrent or complicated osteomyelitis is by local antibiotherapy mediated by suitable bone grafts. ß–Tricalcium Phosphate (ß–TCP) bioceramic is a resorbable bone graft. Its microporosity allows for incorporation of drugs, but a too fast release is often obtained. Complex strategies have been explored to obtain controlled drug release. In this work, plasma polymerization of a biocompatible polymer was investigated on ß-TCP. Polyethyleneglycol (PEG)-like polymer c...
Citació
Khurana, K., Müller, F., Jacobs, K., Canal, C., Ginebra, M.P. Plasma polymerized bioceramics for drug delivery: Do surface changes alter biological behaviour?. "European polymer journal", 1 Octubre 2018, vol. 107, p. 25-33.
Paraules clau
Plasma polymerization ß–Tricalcium phosphate PEG-like polymer Antibiotics Drug release Biocompatibility
Grup de recerca
BBT - Biomaterials, Biomecànica i Enginyeria de Teixits
CREB - Centre de Recerca en Enginyeria Biomedica
CRnE - Centre de Recerca en Ciència i Enginyeria Multiescala de Barcelona

Participants