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Ectopic beats arise from micro-reentries near infarct regions in simulations of a patient-specific heart model

Autor
sachetto, R.; Alonso, S.; Otaviano, F.; Martins , B.; Filipe, J.; Kuehne, T.; Weber, R.
Tipus d'activitat
Article en revista
Revista
Scientific reports
Data de publicació
2018-12-01
Volum
8
Pàgina inicial
16392-1
Pàgina final
16392-14
DOI
https://doi.org/10.1038/s41598-018-34304-y Obrir en finestra nova
Projecte finançador
Ajut per a contractació RYC-2012-11265
Repositori
http://hdl.handle.net/2117/124982 Obrir en finestra nova
URL
https://www.nature.com/articles/s41598-018-34304-y Obrir en finestra nova
Resum
Ectopic beats are known to be involved in the initiation of a variety of cardiac arrhythmias. Although their location may vary, ectopic excitations have been found to originate from infarct areas, regions of micro-fibrosis and other heterogeneous tissues. However, the underlying mechanisms that link ectopic foci to heterogeneous tissues have yet to be fully understood. In this work, we investigate the mechanism of micro-reentry that leads to the generation of ectopic beats near infarct areas usi...
Citació
sachetto, R., Alonso, S., Otaviano, F., Martins , B., Filipe, J., Kuehne, T., Weber, R. Ectopic beats arise from micro-reentries near infarct regions in simulations of a patient-specific heart model. "Scientific reports", 1 Desembre 2018, vol. 8, p. 16392-1-16392-14.
Paraules clau
Computational models, Computational science, Ventricular tachycardia
Grup de recerca
BIOCOM-SC - Grup de Biologia Computacional i Sistemes Complexos

Participants

  • sachetto Oliveira, Rafael  (autor)
  • Alonso Muñoz, Sergio  (autor)
  • Otaviano Campos, Fernando  (autor)
  • Martins Rocha, Bernardo  (autor)
  • Filipe Fernandes, João  (autor)
  • Kuehne, Titus  (autor)
  • Weber dos Santos, Rodrigo  (autor)

Arxius