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Amyloid-like fibrils from a diphenylalanine capped with an aromatic fluorenyl

Author
Martí, D.; Mayans, E.; Gil, A.; Diaz, A.; Jimenez, A.; Yousef, I.; Keridou, I.; Cativiela, C.; Puiggali, J.; Aleman, C.
Type of activity
Journal article
Journal
Langmuir
Date of publication
2018-11-19
Volume
34
Number
50
First page
15551
Last page
15559
DOI
https://doi.org/10.1021/acs.langmuir.8b03378 Open in new window
Repository
http://hdl.handle.net/2117/127843 Open in new window
URL
https://pubs.acs.org/doi/10.1021/acs.langmuir.8b03378 Open in new window
Abstract
The self-assembly behavior of a diphenylalanine amphiphile blocked at the C-terminus with a 9-fluorenylmethyl ester and stabilized at the N-terminus with a trifluoroacetate (TFA) anion, TFA·FF-OFm, has been examined. At low peptide concentration (0.5 mg/mL), long amyloid-like fibrils, which come from the fusion of two or more helical ribbons and/or thinner fibrils, organized in bundles or as individual entities are detected. Microbeam synchrotron radiation infrared spectroscopy has shown that T...
Citation
Martí, D. [et al.]. Amyloid-like fibrils from a diphenylalanine capped with an aromatic fluorenyl. "Langmuir", 19 Novembre 2018, vol. 34, núm. 50, p. 15551-15559.
Group of research
CRnE - Barcelona Research Center in Multiscale Science and Engineering
IMEM-BRT - Innovation in Materials and Molecular Engineering - Biomaterials for Regenerative Therapies
PSEP - Synthetic Polymers: Structure and Properties. Biodegradable Polymers.

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