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A tissue-specific network-based pathway test and application to GWAS data

Author
Picart, S.; Thompson, W.; Buil, A.; Perera, A.
Type of activity
Presentation of work at congresses
Name of edition
VI Jornada de Bioinformàtica i Genòmica
Date of publication
2018
Presentation's date
2018-12-20
Book of congress proceedings
VI Jornada de Bioinformàtica i Genòmica: programa i resums de les comunicacions: Barcelona 20 de desembre de 2018
First page
12
Last page
12
Abstract
Biological pathway analysis is a common approach to relate molecular phenotypes to diseases by including contextual knowledge from annotated comprehensive databases. Finding over-represented biological pathways serves as a quality control and can point towards novel discoveries. The leverage of public tissue-specific interactomes enables including topological patterns to increase the number of findings and their specificity. Unfortunately, most pathway analysis tools do not account for tissue-sp...
Group of research
B2SLab - Bioinformatics and Biomedical Signals Laboratory
CREB - Biomedical Engineering Research Centre

Participants