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The effect of the thermosensitive biodegradable PLGA–PEG–PLGA copolymer on the rheological, structural and mechanical properties of thixotropic self-hardening tricalcium phosphate cement

Author
Vojtova, L.; Michlovska, L.; Valova, K.; Ginebra, M.P.
Type of activity
Journal article
Journal
International journal of molecular sciences
Date of publication
2019-01-17
Volume
20
Number
2
First page
391
Last page
412
DOI
10.3390/ijms20020391
Repository
http://hdl.handle.net/2117/133088 Open in new window
URL
https://www.mdpi.com/1422-0067/20/2/391 Open in new window
Abstract
The current limitations of calcium phosphate cements (CPCs) used in the field of bone regeneration consist of their brittleness, low injectability, disintegration in body fluids and low biodegradability. Moreover, no method is currently available to measure the setting time of CPCs in correlation with the evolution of the setting reaction. The study proposes that it is possible to improve and tune the properties of CPCs via the addition of a thermosensitive, biodegradable, thixotropic copolymer ...
Citation
Vojtova, L. [et al.]. The effect of the thermosensitive biodegradable PLGA–PEG–PLGA copolymer on the rheological, structural and mechanical properties of thixotropic self-hardening tricalcium phosphate cement. "International journal of molecular sciences", 17 Gener 2019, vol. 20, núm. 2, p. 391-412.
Keywords
biocompatibility, injectable bone cements, kinetics, morphology, rheology, thixotropic
Group of research
BBT - Biomaterials, Biomechanics and Tissue Engineering
CREB - Biomedical Engineering Research Centre
CRnE - Barcelona Research Center in Multiscale Science and Engineering

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