Continuous monitoring of biofilm growth and inhibition based on QCM resonators
Total activity: 1
Type of activity
AGENCIA ESTATAL DE INVESTIGACION
Funding entity code
The search of systems for the early diagnosis and eradication of biofilms produced by microorganisms is a subject of curren! research and great interest. Microorganisms, such as bacteria, develop in their ecosystems in a communitarian way, forming colonies. In most cases, these colonies adhere themselves at interfaces of the host system in the form of biofilms, which help them to retain nutrients and protect themselves from environmental hazards. The robustness and rapid adaptation to the environment of these communities seriously hinders their removal with biocidal agents such as antibiotics. Biofilms are particularly harmful when growing on implanted materials (for example, in prosthesis),ln this sense, the availability of electronic systems that allow the continuous monitoring of growth and, if necessary, the inhibition of these biofilms will be of great help for the progress of this research. In the project a novel proposal is made seeking to develop a biofilm non-invasive and on-line monitoring technique by designing a multichannel measurement system based on quartz crystal resonators. This characterization system based on resonators will contribute significantly to the knowledge of the biofilm growth dynamics, accelerating the research on diagnostic, treatment and prevention techniques.
Amer, M.; Turo, A.; Salazar, J.; Berlanga, L.; Garcia, M.; Chavez-Dominguez, J. A. IEEE transactions on instrumentation and measurement Vol. 69, num. 6, p. 2982-2995 DOI: 10.1109/TIM.2019.2929280 Date of publication: 2020-06 Journal article