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Quantitative cytologic descriptors to differentiate CLL, sézary, granular, and villous lymphocytes through image analysis

Author
Puigvi, L.; Merino, A.; Alferez, E.; Boldú, L.; Acevedo, A.; Rodellar, J.
Type of activity
Journal article
Journal
American journal of clinical pathology
Date of publication
2019-06-05
Volume
152
Number
1
First page
74
Last page
85
DOI
10.1093/ajcp/aqz025
URL
https://academic.oup.com/ajcp/article-abstract/152/1/74/5467104 Open in new window
Abstract
We aimed to find descriptors to identify chronic lymphocytic leukemia (CLL), Sézary, granular, and villous lymphocytes among normal and abnormal lymphocytes in peripheral blood. Methods Image analysis was applied to 768 images from 15 different types of lymphoid cells and monocytes to determine four discriminant descriptors. For each descriptor, numerical scales were obtained using 627 images from 79 patients. An assessment of the four descriptors was performed using smears from 209 new patien...
Group of research
CoDAlab - Control, Dynamics and Applications

Participants