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The conduct and reporting of mediation analysis in recently published randomized controlled trials: results from a methodological systematic review

Author
Vo, T.; Superchi, C.; Boutron, I.; Vansteelandt, S.
Type of activity
Journal article
Journal
Journal of clinical epidemiology
Date of publication
2020-01-01
Volume
117
First page
78
Last page
88
DOI
10.1016/j.jclinepi.2019.10.001
Project funding
Methods in research on research
URL
https://www.sciencedirect.com/science/article/pii/S0895435619303464 Open in new window
Abstract
Objectives To describe the methodological characteristics of mediation analyses (MAs) reported in recent randomized controlled trials (RCTs) and to propose recommendations on the planning, conduct, and reporting of MAs in practice. Study Design and Setting We conducted a systematic review by searching MEDLINE (January 1, 2017, to December 1, 2018) for all reports of RCTs or secondary analyses of previously published RCTs that reported a MA. Two reviewers independently screened the title, abstrac...
Keywords
Counterfactual-based mediation approaches, Mediation analysisTraditional mediation approaches, Randomized controlled trial, ReportingSystematic review
Group of research
GNOM - Mathematical Optimization Group

Participants

  • Vo, Tat-Thang  (author)
  • Superchi, Cecilia  (author)
  • Boutron, Isabelle  (author)
  • Vansteelandt, Stijn  (author)