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Speech pause distribution as an early marker for Alzheimer’s disease

Author
Pastoriza, P.; González, I.; Diéguez-Vide, F.; Gómez , M.; Geladó, S.; Bello-López, J.; Ávila-Rivera, A.; Matías-Guiu, J.; Pytel, V.; Hernandez Fernandez, A.
Type of activity
Report
Date
2021-01
DOI
10.1101/2020.12.28.20248875
Project funding
RCO03080 Lingüística quantitativa
Repository
http://hdl.handle.net/2117/336799 Open in new window
URL
https://www.medrxiv.org/content/10.1101/2020.12.28.20248875v1.full.pdf+html Open in new window
Abstract
Background: Pause duration analysis is a common feature in the study of discourse in Alzheimer’s disease (AD) and may also be helpful for its early detection. However, studies involving patients at the preclinical stage of mild cognitive impairment (MCI) have yielded varying results. Objectives: To characterize the probability density distribution of speech pause duration in AD, two multi-domain amnestic MCI patients (with memory encoding deficits, a-mdMCI-E, and only with retrieval impairmen...
Citation
Pastoriza, P. [et al.]. Speech pause distribution as an early marker for Alzheimer's disease. 2021. DOI 10.1101/2020.12.28.20248875.
Keywords
Alzheimer’s disease, Fluency, Mild cognitive impairment, Natural language processing, Speech, Statistical distributions
Group of research
LARCA - Laboratory of Relational Algorithmics, Complexity and Learnability

Participants

  • Pastoriza-Domínguez, Patricia  (author)
  • González Torre, Ivan  (author)
  • Diéguez-Vide, Faustino  (author)
  • Gómez Ruiz, María Isabel  (author)
  • Geladó Muñoz, Sandra  (author)
  • Bello-López, Joan  (author)
  • Ávila-Rivera, Asunción  (author)
  • Matías-Guiu, Jordi  (author)
  • Pytel Córdoba, Vanesa  (author)
  • Hernandez Fernandez, Antonio  (author)