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Uncovering de novo gene birth in yeast using deep transcriptomics

Author
Blevins, W.; Ruiz, J.; Messeguer, X.; Blasco, B.; Villanueva, J.; Espinar, L.; Díez, J.; Carey, L.; Albà, M.
Type of activity
Journal article
Journal
Nature communications
Date of publication
2021-01-27
Volume
12
Number
article 604
First page
1
Last page
13
DOI
10.1038/s41467-021-20911-3
Project funding
Formal reasoning for enabling and emerging technologies
Logic-Based Smart Solutions
Repository
http://hdl.handle.net/2117/343173 Open in new window
URL
https://www.nature.com/articles/s41467-021-20911-3 Open in new window
Abstract
De novo gene origination has been recently established as an important mechanism for the formation of new genes. In organisms with a large genome, intergenic and intronic regions provide plenty of raw material for new transcriptional events to occur, but little is know about how de novo transcripts originate in more densely-packed genomes. Here, we identify 213 de novo originated transcripts in Saccharomyces cerevisiae using deep transcriptomics and genomic synteny information from multiple yeas...
Citation
Blevins, W. [et al.]. Uncovering de novo gene birth in yeast using deep transcriptomics. "Nature communications", 27 Gener 2021, vol. 12, article 604, p. 1-13.
Group of research
ALBCOM - Algorithms, Computational Biology, Complexity and Formal Methods
CEBIM - Molecular Biotechnology Centre

Participants

  • Blevins, William R.  (author)
  • Ruiz Orera, Jorge  (author)
  • Messeguer Peypoch, Xavier  (author)
  • Blasco Moreno, Bernat  (author)
  • Villanueva Cañas, José Luis  (author)
  • Espinar Calvo, Lorena  (author)
  • Díez Antón, Juana  (author)
  • Carey, Lucas B.  (author)
  • Albà Soler, M. Mar  (author)

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