In the last 60 years, the percentage of urban population increased from the 33% to the 55% of the total and it is expected to reach the 70% by 2050. Densely populated cities amplify the vulnerability and health risk of more disadvantaged groups to the impact of climate change. Health and wellbeing in buildings and public spaces are increasingly influential factors of the sustainability of the built environment, which should be addressed combining energy efficient solutions with an human-centred design approach. Compact cities in the Mediterranean region have proved to be efficient models in terms of energy use for transportation and buildings. However, the high efficiency of urban compactness may also result in a lower resilience of the urban environment in facing disrupting events. In fact, as highlighted by the COVID-19 pandemic, the quality of both indoor and outdoor spaces plays a pivotal role on the physical and mental health of urban dwellers and on the ability of urban systems to adapt to changing conditions. The quality of outdoor has been much less investigated than the health and comfort in indoor spaces. However, the utility of intermediate spaces like balconies and rooftops was utterly demonstrated during the pandemic, unveiling that the connection with the exterior is a fundamental need for urban citizens. High quality public spaces can provide a liveable outdoor environment and promote a healthy lifestyle in dense urban areas. However, when the public space is scarce and neglected, a common condition in vulnerable neighbourhoods, the overall quality of urban life lowers substantially. This project aims at defining a set of indicators to assess the environmental quality of outdoor spaces in relation to their potential to improve the quality of life of vulnerable groups of population. Particular attention will be payed to summer periods. In fact, thermal comfort and urban health are more concerning due to the combined effect of the urban heat island and more frequent and intense heat waves. This project intends to characterise these urban havens in correlation to existing indexes of vulnerability in order to identify the areas where are more lacking. Microclimate effect on users comfort will be evaluated by adopting a holistic and human-centric point of view. The characteristics of the urban microclimate will be assessed in relation to the sensation and perception of people at the street level, considering thermal, visual and acoustic comfort and air quality. The environmental quality of urban spaces will be assessed considering key features of the urban fabric that influence urban microclimate, based on scientific literature and previous work of the research group. These are: surface permeability, presence of different species of vegetation, urban morphology, solar access of streets and facades, lighting conditions, ventilation, anthopogenic heat from traffic and buildings HVAC systems and reflectivity of materials. The novelty of this project is to include in the same georeferenced database the vulnerability indicators currently already mapped with the microclimatic data of the selected case studies. The result should provide guidelines to help in the decision making process when favouring the implementation of spaces that increase the resilience of the city (urban havens) where its effect are most beneficial for the population (vulnerable neighbourhoods) and fot the urban system at whole.