Loading...
Loading...

Go to the content (press return)

Enzyme-decorated mesoporous silica nanoparticles for elimination of antibiotic resistant pseudomonas aeruginosa biofilms

Author
Asenova, A.; Ivanova, K.; Tzanov, T.
Type of activity
Presentation of work at congresses
Name of edition
AAAFM UCLA International Conference on Advances in Functional Materials 2021
Date of publication
2021
Presentation's date
2021-08-18
Book of congress proceedings
AAAFM-UCLA International Conference on Advances in Functional Materials 2021: abstract book
First page
88
Last page
88
Repository
https://aaafm.org/ucla2021/wp-content/uploads/2021/04/Abstract-Book.pdf Open in new window
Abstract
Bacterial antibiotic resistance is frequently associated with their ability to form biofilms, acting as a physical barrier that limit the antibiotics penetration and bacterial eradication. Most of the existing strategies aim to inhibit bacterial growth and prevent the biofilm formation, but they become ineffective once the biofilm is well-established. Herein, stimuli-responsive mesoporous silica nanoparticles (MSNPs) were developed for treatment of antibiotic resistant Pseudomonas aeruginosa (P....
Keywords
Biofilm eradication, Biofilm-degrading enzyme, Smart mesoporous silica nanoparticles, Stimuliresponsive nanosystem, drug delivery
Group of research
GBMI - Molecular and Industrial Biotechnology Group

Participants