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Nadir CD4 cell count predicts neurocognitive impairment in HIV-infected patients

Author
Muñoz-Moreno, J.A.; Fumaz, C.R.; Ferrer, M.; Prats, A.; Negredo, E.; Garolera, M.; Perez, N.; Molto, J.; Gómez Melis, Guadalupe; Clotet, B.
Type of activity
Journal article
Journal
AIDS research and human retroviruses
Date of publication
2008-10
Volume
24
Number
10
First page
1301
Last page
1307
DOI
https://doi.org/10.1089/aid.2007.0310 Open in new window
URL
https://www.ncbi.nlm.nih.gov/pubmed/18844464 Open in new window
Abstract
Though antiretroviral therapy attenuates neurocognitive disruption, impairment is still observed. We studied the nadir CD4 cell count as a predictor of neurocognitive changes. This cross-sectional study assessed 64 HIV-infected patients in two groups: G1 (n = 26, nadir CD4 < or =200 cells/ml) and G2 (n = 38, nadir CD4 >200 cells/ml). Percentages of patients showing neurocognitive impairment were compared according to different nadir CD4 cutoffs (200, 250, 300, and 350 cells/ml). From G2, we also...
Group of research
GRBIO - Biostatistics and Bioinformatics Research Group

Participants

  • Muñoz Moreno, Jose Antonio  (author)
  • Rodriguez Fumaz, Carmina  (author)
  • Ferrer Lasala, Maria Jose  (author)
  • Prats París, Anna  (author)
  • Negredo Puigmal, Eugènia  (author)
  • Garolera Freixa, Maite  (author)
  • Perez Alvarez, Nuria  (author)
  • Molto Marhuenda, Jose  (author)
  • Gomez Melis, Guadalupe  (author)
  • Clotet Sala, Bonaventura  (author)