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Calcium alternans produced by increased sarcoplasmic reticulum refractoriness

Author
Rodriguez Cantalapiedra, I.; Lugo, C.A.; Peñaranda, A.; Echebarria, B.
Type of activity
Presentation of work at congresses
Name of edition
Computing in Cardiology 2011
Date of publication
2011
Presentation's date
2011-09-12
Book of congress proceedings
Proceedings: computing in cardiology
First page
645
Last page
648
Publisher
IEEE Computer Society Publications
Repository
http://hdl.handle.net/2117/16016 Open in new window
URL
http://cataleg.upc.edu/record=b1383765~S1*cat Open in new window
Abstract
Despite the important role of electro-mechanical alternans in cardiac arrhythmogenesis, its molecular origin is not well understood. In this paper we want to study alternans that can be associated with alternations in the cytosolic calcium transient. To this end we study particularly, how a malfunction of Ryanodine Receptor (RyR) recovery time from inactivation may induce beatto- beat alternations in intracellular calcium concentration and how this could affect the stimulus propagation in inhomo...
Citation
Cantalapiedra, I. R. [et al.]. Calcium alternans produced by increased sarcoplasmic reticulum refractoriness. A: Computing in Cardiology. "Proceedings: computing in cardiology". Hangzhou: IEEE Computer Society Publications, 2011, p. 645-648.
Group of research
ANCORA - Anàlisi i control del ritme cardíac
BIOCOM-SC - Computational Biology and Complex Systems Group
GICITED - Interdisciplinary Group on Building Scienceand and Technology

Participants